Asparagine

In proteins, asparagine may have different functions. This is a polar residue, which may be placed on a polar exterior of a globular protein. The amino acid side chain has both, hydrogen bond donor (NH2) and acceptor (C=O) places, this can be utilized for hydrogen bonding, or in catalysis. It is also common that the nitrogen atom of asparagine is glycosylated.
Interesting readings:
- Lea, P. G. et al. Asparagine in plants. Ann, Appl. Biol., 150, 2007, 1-26, doi: 10.1111/j.1744-7348.2006.00104.x
- Imperiali, B. and Rickert, K. W. Conformational implications of asparagine-linked glycosylation. Proc. Natl. Acad. Sci. USA, 92, 1995, 97-101, doi: 10.1073/pnas.92.1.97
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