We live in the “Alanine world” bubble!

The Alanine World Model, proposed by Vladimir Kubyshkin and Nediljko Budisa, suggests that L-alanine served as the fundamental scaffold in the early evolution of proteins. Instead of a random evolution of protein biochemistry, this model argues that life's genetic code, metabolism, and protein folding were systematically built upon alanine and its derivatives. This foundation supported the emergence of α-helices and stable protein architectures, ultimately shaping biological complexity.

While Earth favored the Alanine World, the model suggests that alternative biochemical "worlds" (e.g., Proline World or Sarcosine World) could arise under different planetary or synthetic conditions. As part of Synthetic Biology and origins-of-life research, this model challenges the traditional Protein World concept, offering new perspectives on life's evolution both on Earth and elsewhere.